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Betamethasone Valerate (Topical Application Route) Description and Brand Names - Mayo Clinic.Betamethasone: Uses, types, warnings, and side effects |
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Betamethasone valerate cream usp .1 -
- Generic Betamethasone Cream & Ointment
Thus, occlusive dressings may be a valuable therapeutic adjunct for treatment of resistant dermatoses. Once absorbed through the skin, topical corticosteroids are handled through pharmacokinetic pathways similar to systemically administered corticosteroids. Corticosteroids are bound to plasma proteins in varying degrees.
Corticosteroids are metabolized primarily in the liver and are then excreted by the kidneys. Some of the topical corticosteroids and their metabolites are also excreted into the bile.
Topical corticosteroids are indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Topical corticosteroids are contraindicated in those patients with a history of hypersensitivity to any of the components of the preparation. Systemic absorption of topical corticosteroids has produced reversible hypothalamic-pituitary-adrenal HPA axis suppression, manifestations of Cushing's syndrome, hyperglycemia, and glucosuria in some patients.
Conditions which augment systemic absorption include the application of the more potent steroids, use over large surface areas, prolonged use, and the addition of occlusive dressings. Therefore, patients receiving a large dose of a potent topical steroid applied to a large surface area should be evaluated periodically for evidence of HPA axis suppression by using the urinary free cortisol and ACTH stimulation tests.
If HPA axis suppression is noted, an attempt should be made to withdraw the drug, to reduce the frequency of application, or substitute to a less potent steroid.
Recovery of HPA axis function is generally prompt and complete upon discontinuation of the drug. Infrequently, signs and symptoms of steroid withdrawal may occur, requiring supplemental systemic corticosteroids.
If irritation develops, topical corticosteroids should be discontinued and appropriate therapy instituted. In the presence of dermatological infections, the use of an appropriate antifungal or antibacterial agent should be instituted.
If a favorable response does not occur promptly, the corticosteroid should be discontinued until the infection has been adequately controlled. Patients using topical corticosteroids should receive the following information and instructions: 1.
This medication is to be used as directed by the physician.. Doctors can prescribe Sernivo spray for up to 4 weeks. According to the directions, people should apply the spray to the affected area twice daily and rub it in gently. People use Luxiq on their scalps twice a day.
The foam will melt once it comes into contact with a warm surface, so people cannot apply this product directly onto their hands. Instead, doctors instruct people to apply a small amount of Luxiq to a cold surface.
From there, they can pick up a small amount with their fingers and gently massage it into the affected area of skin. When doctors administer betamethasone injections , people may report a range of side effects that affect different parts of the body, including the:. People may also report side effects when using betamethasone lotion or ointment on their skin. The most common side effects that people report include:. Betamethasone dipropionate cream is a weaker corticosteroid than the ointment, and people report fewer side effects.
In a study of adults using betamethasone dipropionate cream, only one person experienced an adverse effect, which was a stinging sensation. Burning and stinging of the skin can also occur when people use betamethasone valerate aerosol foam.
When people use betamethasone dipropionate spray , the most common side effects are:. Rarely, people who use betamethasone valerate products may experience localized side effects on the area where they applied the product. These may include:. Anyone who has a history of allergic reactions to betamethasone or any ingredient in betamethasone injections should avoid this treatment.
When prescribing topical betamethasone, doctors should not give this treatment to any person with a history of allergic reactions to betamethasone or any other corticosteroid. In rare cases, a person who uses corticosteroids on their skin may experience hypothalamic-pituitary-adrenal HPA axis suppression and adrenal insufficiency. The HPA axis produces steroids that control and regulate many body functions.
When people use corticosteroids, the body may stop producing steroids. As a result, the adrenal glands may shrink and stop working properly. Betamethasone skin treatments are used to treat itching, swollen and irritated skin. They can help with conditions such as eczema , contact dermatitis and psoriasis.
Betamethasone skin treatments are available on prescription only. They come as:. They're stronger than some other treatments, such as hydrocortisone skin creams. Betamethasone is usually prescribed when other medicines have not worked.
Betamethasone is a type of medicine known as a steroid also called a corticosteroid. This is not the same as an anabolic steroid. Sometimes betamethasone is mixed with an antibiotic called fusidic acid. This is used to treat bacterial skin infections. It also comes as an eye ointment; drops for your eyes, ears or nose; tablets and injections. Most adults aged 18 or over can use betamethasone skin treatments. Medicated plasters are suitable for adults only. Most other betamethasone skin treatments can be used by children over the age of 1 year.
Occasionally a specialist may prescribe them for a younger child. However, some betamethasone creams and foams will only be prescribed for children aged 6 years and older. Betamethasone may not be suitable for some people.
Tell a pharmacist or doctor before using it if you :. Always follow the instructions from a pharmacist, doctor or the leaflet that comes with your medicine. Creams are better for skin that is moist and weepy. Ointments are thicker and greasier, and are better for dry or flaky areas of skin.
You will usually use betamethasone skin cream or ointment once or twice a day. The amount of cream or ointment you need to use is sometimes measured in fingertip units. This is the amount you can squeeze onto the end of your finger. A fingertip unit of cream is generally enough to treat an area that's twice the size of the palm of your hand. For children, the right amount of cream or ointment depends on their age. A doctor or pharmacist can advise you.
If you are prescribed a combination cream containing betamethasone and an antibiotic, follow the instructions that come with your medicine. Do not use betamethasone skin cream or ointment at the same time as any other creams or ointments, such as a moisturiser or emollient. Wait at least 30 minutes before using any other skin product after you put on betamethasone cream or ointment. Skin creams can dry onto your clothes and bedding.
This makes them more likely to catch fire. Avoid naked flames. If you need to use a dressing, like a bandage or plaster, wait at least 10 minutes after putting betamethasone on. If you're treating a child, do not cover the cream or ointment with dressings or bandages. This can cause more medicine to pass through the skin and into the bloodstream, leading to a higher chance of side effects. If your doctor has prescribed it to treat very severe nappy rash, ask them how much to use and how long to use it for.
Skin lotions can dry onto your clothes and bedding. You will usually use the lotion twice a day. You can use it once a day or less often when your condition improves. If you have washed your hair, dry it properly before using the scalp lotion. You can use the foam up to twice a day. Medicated plasters are for small areas of skin and thickened skin affected by psoriasis.
Do not reuse plasters. Use a new plaster on the same patch of skin every 24 hours. Wait at least 30 minutes between taking off an old plaster and putting on a new one.
Do not get the plaster wet. It's best to have a shower or bath after taking off the old plaster and before putting on a new one. Most people only need to use betamethasone skin treatments for a short time. Stop as soon as your skin is better. Sometimes you only need to use the skin treatments for a few days.
Our team of doctors and pharmacists, and our support staff, are all UK-based. We're on hand to offer free support and advice by email and telephone Mon - Fri - This treatment requires an online consultation for review by our medical team.
The decision to supply the specific treatment and quantity requested will be based on whether our medical team are satisfied that it will be safe, appropriate, and effective. Betamethasone cream and ointment are effective topical treatments for inflamed skin. Using the active ingredient known as betamethasone, the cream will reduce any itching, inflammation and redness associated with common skin conditions such as:.
Betamethasone cream is an unbranded generic version of Betnovate and both contain the same active ingredient. Betamethasone falls into the category of topical corticosteroid or topical steroids. Topical steroids such as this product should be used in addition to your usual moisturiser in order to treat and manage your skin condition effectively. While this treatment is not a cure for your skin condition, it will help you to manage the symptoms, drastically improving your quality of life.
Using betamethasone has been proven to treat afflictions all throughout the body, from your scalp, all the way to the soles of your feet. Inflammation can arise for a number of reasons, usually as a result of a skin irritant or allergic reaction. When your body detects such an inflammation it will release various chemicals which cause your blood vessels to widen, creating the swollen, itchy, redness, known as inflammation.
Once Betamethasone has been topically applied it will begin to work directly within your cells, decreasing the inflammatory chemicals and reducing the swelling and redness associated with your skin condition. The cream can also be used for other inflammations as well, such as allergies or irritants, bodily reactions to insect bites and stings, as well as rashes caused by local problems.
The active ingredient Betamethasone is available in a wide variety of preparations. If your skin is moist or weeping then you will usually be prescribed Betamethasone cream.
Betamethasone Valerate Cream and Ointment contain betamethasone valerate USP, a synthetic adrenocorticosteroid for dermatologic use. Betamethasone, an analog of prednisolone, has a high degree of glucocorticoid activity and a slight degree of mineralocorticoid activity. Betamethasone valerate is a white to practically white odorless crystalline powder practically insoluble in water, freely soluble in acetone and chloroform, soluble in alcohol, and slightly soluble in benzene and ether.
The structural formula is: Each gram of the 0. Each gram of the 0. Topical corticosteroids share anti-inflammatory, antipruritic and vasoconstrictive actions. The mechanism of anti-inflammatory activity of the topical corticosteroids is unclear. There is some evidence to suggest that a recognizable correlation exists between vasoconstrictor potency and therapeutic efficacy in man.
The extent of percutaneous absorption of topical corticosteroids is determined by many factors including the vehicle, the integrity of the epidermal barrier, and the use of occlusive dressings. Topical corticosteroids can be absorbed from normal intact skin. Occlusive dressings substantially increase the percutaneous absorption of topical corticosteroids. Thus, occlusive dressings may be a valuable therapeutic adjunct for treatment of resistant dermatoses.
Once absorbed through the skin, topical corticosteroids are handled through pharmacokinetic pathways similar to systemically administered corticosteroids. Corticosteroids are bound to plasma proteins in varying degrees. Corticosteroids are metabolized primarily in the liver and are then excreted by the kidneys.
Some of the topical corticosteroids and their metabolites are also excreted into the bile. Topical corticosteroids are indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Topical corticosteroids are contraindicated in those patients with a history of hypersensitivity to any of the components of the preparation.
Systemic absorption of topical corticosteroids has produced reversible hypothalamic-pituitary-adrenal HPA axis suppression, manifestations of Cushing's syndrome, hyperglycemia, and glucosuria in some patients. Conditions which augment systemic absorption include the application of the more potent steroids, use over large surface areas, prolonged use, and the addition of occlusive dressings.
Therefore, patients receiving a large dose of a potent topical steroid applied to a large surface area should be evaluated periodically for evidence of HPA axis suppression by using the urinary free cortisol and ACTH stimulation tests.
If HPA axis suppression is noted, an attempt should be made to withdraw the drug, to reduce the frequency of application, or substitute to a less potent steroid. Recovery of HPA axis function is generally prompt and complete upon discontinuation of the drug. Infrequently, signs and symptoms of steroid withdrawal may occur, requiring supplemental systemic corticosteroids.
If irritation develops, topical corticosteroids should be discontinued and appropriate therapy instituted. In the presence of dermatological infections, the use of an appropriate antifungal or antibacterial agent should be instituted. If a favorable response does not occur promptly, the corticosteroid should be discontinued until the infection has been adequately controlled.
Patients using topical corticosteroids should receive the following information and instructions: 1. This medication is to be used as directed by the physician. It is for external use only. Avoid contact with the eyes.
Patients should be advised not to use this medication for any disorder other than that for which it was prescribed. The treated skin area should not be bandaged or otherwise covered or wrapped as to be occlusive unless directed by the physician.
Patients should report any signs of local adverse reactions especially under occlusive dressing. Parents of pediatric patients should be advised not to use tight-fitting diapers or plastic pants on a child being treated in the diaper area, as these garments may constitute occlusive dressings.
Long-term animal studies have not been performed to evaluate the carcinogenic potential or the effect on fertility of topical corticosteroids. Studies to determine mutagenicity with prednisolone and hydrocortisone have revealed negative results. Teratogenic Effects — Pregnancy Category C Corticosteroids are generally teratogenic in laboratory animals when administered systemically at relatively low dosage levels.
The more potent corticosteroids have been shown to be teratogenic after dermal application in laboratory animals. There are no adequate and well-controlled studies in pregnant women on teratogenic effects from topically applied corticosteroids. Therefore, topical corticosteroids should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Drugs of this class should not be used extensively on pregnant patients, in large amounts, or for prolonged periods of time.
It is not known whether topical administration of corticosteroids could result in sufficient systemic absorption to produce detectable quantities in breast milk. Systemically administered corticosteroids are secreted into breast milk in quantities not likely to have a deleterious effect on the infant. Nevertheless, caution should be exercised when topical corticosteroids are administered to a nursing woman. Pediatric patients may demonstrate greater susceptibility to topical corticosteroid-induced HPA axis suppression and Cushing's syndrome than mature patients because of a larger skin surface area to body weight ratio.
Hypothalamic-pituitary-adrenal HPA axis suppression, Cushing's syndrome, and intracranial hypertension have been reported in children receiving topical corticosteroids. Manifestations of adrenal suppression in children include linear growth retardation, delayed weight gain, low plasma cortisol levels, and absence of response to ACTH stimulation.
Manifestations of intracranial hypertension include bulging fontanelles, headaches, and bilateral papilledema. Administration of topical corticosteroids to pediatric patients should be limited to the least amount compatible with an effective therapeutic regimen. Chronic corticosteroid therapy may interfere with the growth and development of children.
The following local adverse reactions are reported infrequently with topical corticosteroids, but may occur more frequently with the use of occlusive dressings.
These reactions are listed in an approximate decreasing order of occurrence: burning, itching, irritation, dryness, folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, maceration of the skin, secondary infection, skin atrophy, striae and miliaria.
Apply a thin film of Betamethasone Valerate Cream or Ointment to the affected skin areas one to three times a day. Dosage once or twice a day is often effective.
Distributed by:. Pharmacokinetics The extent of percutaneous absorption of topical corticosteroids is determined by many factors including the vehicle, the integrity of the epidermal barrier, and the use of occlusive dressings. General Systemic absorption of topical corticosteroids has produced reversible hypothalamic-pituitary-adrenal HPA axis suppression, manifestations of Cushing's syndrome, hyperglycemia, and glucosuria in some patients.
Information for Patients Patients using topical corticosteroids should receive the following information and instructions: 1. Carcinogenesis, Mutagenesis and Impairment of Fertility Long-term animal studies have not been performed to evaluate the carcinogenic potential or the effect on fertility of topical corticosteroids. Pregnancy Teratogenic Effects — Pregnancy Category C Corticosteroids are generally teratogenic in laboratory animals when administered systemically at relatively low dosage levels.
Nursing Mothers It is not known whether topical administration of corticosteroids could result in sufficient systemic absorption to produce detectable quantities in breast milk. Pediatric Use Pediatric patients may demonstrate greater susceptibility to topical corticosteroid-induced HPA axis suppression and Cushing's syndrome than mature patients because of a larger skin surface area to body weight ratio.
Distributed by: Cosette Pharmaceuticals, Inc. South Plainfield, NJ Rev. Cosette Pharmaceuticals, Inc. Product Information. Inactive Ingredients. Product Characteristics. Marketing Information. Labeler - Cosette Pharmaceuticals, Inc.
Registrant - Cosette Pharmaceuticals, Inc.
Betamethasone Valerate Cream and Ointment contain betamethasone valerate USP, a synthetic adrenocorticosteroid for dermatologic use. Betamethasone, an analog of. 1. About betamethasone for skin. Betamethasone skin treatments are used to treat itching, swollen and irritated skin. They can help with conditions such as. Creams and lotions People can apply a few drops of betamethasone dipropionate or betamethasone valerate lotion to the affected area once or. This medication is used to treat a variety of skin conditions (such as eczema, dermatitis, allergies, rash). Betamethasone reduces the swelling, itching, and. Betamethasone valerate is a potent topical corticosteroid indicated for adults, elderly and children over 1 year for the relief of the inflammatory and. This is not the same as an anabolic steroid. A person should ask their doctor or pharmacist for specific instructions.Back to Medicines A to Z. Betamethasone skin treatments are used to treat itching, swollen and irritated skin. They can help with conditions such as eczema , contact dermatitis and psoriasis. Betamethasone skin treatments are available on prescription only. They come as:. They're stronger than some other treatments, such as hydrocortisone skin creams.
Betamethasone is usually prescribed when other medicines have not worked. Betamethasone is a type of medicine known as a steroid also called a corticosteroid. This is not the same as an anabolic steroid. Sometimes betamethasone is mixed with an antibiotic called fusidic acid. This is used to treat bacterial skin infections. It also comes as an eye ointment; drops for your eyes, ears or nose; tablets and injections.
Most adults aged 18 or over can use betamethasone skin treatments. Medicated plasters are suitable for adults only. Most other betamethasone skin treatments can be used by children over the age of 1 year. Occasionally a specialist may prescribe them for a younger child. However, some betamethasone creams and foams will only be prescribed for children aged 6 years and older. Betamethasone may not be suitable for some people. Tell a pharmacist or doctor before using it if you :.
Always follow the instructions from a pharmacist, doctor or the leaflet that comes with your medicine. Creams are better for skin that is moist and weepy. Ointments are thicker and greasier, and are better for dry or flaky areas of skin. You will usually use betamethasone skin cream or ointment once or twice a day. The amount of cream or ointment you need to use is sometimes measured in fingertip units. This is the amount you can squeeze onto the end of your finger.
A fingertip unit of cream is generally enough to treat an area that's twice the size of the palm of your hand. For children, the right amount of cream or ointment depends on their age. A doctor or pharmacist can advise you. If you are prescribed a combination cream containing betamethasone and an antibiotic, follow the instructions that come with your medicine. Do not use betamethasone skin cream or ointment at the same time as any other creams or ointments, such as a moisturiser or emollient.
Wait at least 30 minutes before using any other skin product after you put on betamethasone cream or ointment. Skin creams can dry onto your clothes and bedding. This makes them more likely to catch fire. Avoid naked flames. If you need to use a dressing, like a bandage or plaster, wait at least 10 minutes after putting betamethasone on.
If you're treating a child, do not cover the cream or ointment with dressings or bandages. This can cause more medicine to pass through the skin and into the bloodstream, leading to a higher chance of side effects. If your doctor has prescribed it to treat very severe nappy rash, ask them how much to use and how long to use it for. Skin lotions can dry onto your clothes and bedding.
You will usually use the lotion twice a day. You can use it once a day or less often when your condition improves. If you have washed your hair, dry it properly before using the scalp lotion.
You can use the foam up to twice a day. Medicated plasters are for small areas of skin and thickened skin affected by psoriasis. Do not reuse plasters. Use a new plaster on the same patch of skin every 24 hours. Wait at least 30 minutes between taking off an old plaster and putting on a new one.
Do not get the plaster wet. It's best to have a shower or bath after taking off the old plaster and before putting on a new one. Most people only need to use betamethasone skin treatments for a short time.
Stop as soon as your skin is better. Sometimes you only need to use the skin treatments for a few days. If you're using the scalp foam, or are using betamethasone on your face, ask your doctor or pharmacist how long to use it for. If you're using the cream, ointment or lotion, tell your doctor if your skin gets worse or does not improve within 2 to 4 weeks or 5 days for a child.
Children must not use the scalp application or foam for more than 5 to 7 days follow the instructions that come with the medicine. Using more than the recommended amount of your betamethasone skin treatment is unlikely to harm you. If you forget to use your betamethasone skin treatment, do not worry. Use it as soon as you remember unless it's nearly time for your next dose.
In this case, skip the missed dose and apply the next one at the usual time. Betamethasone skin treatments are unlikely to cause any side effects if you follow the instructions. You're more likely to have side effects if you use it on large areas of skin for long periods of time, or on sensitive skin areas such as the face, or under dressings or nappies.
Some people get a burning or stinging feeling for a few minutes when they put betamethasone on their skin. This stops happening after you've been using it for a few days. Serious side effects are rare. They happen to less than 1 in 10, people who use betamethasone skin treatments. You're more likely to have a serious side effect if you use betamethasone on a large area of skin for a long time. Using betamethasone for a long time can make your skin thinner or cause stretch marks.
Stretch marks are likely to be permanent, but they usually fade over time. In very rare cases, using betamethasone for a long time can slow the normal growth of children and teenagers. Your child's doctor will monitor their height and weight carefully if they need to use this medicine often. This will help them to notice if your child's growth is being affected and they can change the treatment if needed.
Talk to your doctor if you're worried. They will be able to explain the benefits and risks of your child using betamethasone. It happens rarely, but it is possible to have a serious allergic reaction anaphylaxis to betamethasone. These are not all the side effects of betamethasone. For a full list, see the leaflet inside your medicine packet. Betamethasone is not usually recommended for use when pregnant. A dermatologist skin care specialist may prescribe it if they feel the benefits outweigh the risks.
Small amounts of betamethasone used on small areas of skin are unlikely to cause any problems in pregnancy. There's not enough research into betamethasone to know if it's safe to use larger amounts in pregnancy. If you're using betamethasone cream or ointment on your breasts, wash off any medicine from your breast, then wash your hands before feeding your baby.
It's usually better to use cream rather than ointment when breastfeeding, as it's easier to wash off. For more information about how betamethasone can affect you and your baby during pregnancy , read this leaflet on the Best Use of Medicines in Pregnancy BUMPs website. It's very unlikely that other medicines will affect the way betamethasone skin treatments work. If you're also using any other skin treatment, make sure you wait about 30 minutes between using betamethasone and using the other skin treatment.
There's very little information about taking herbal remedies and supplements while using betamethasone. Ask a pharmacist for advice. Tell your doctor or pharmacist if you're taking any other medicines, including herbal medicines, vitamins or supplements. Betamethasone is a steroid also called a corticosteroid. Steroids help to reduce inflammation in the skin and other parts of your body.
Skin gets inflamed when an allergic reaction or irritation causes chemicals to be released in the skin. These make your blood vessels widen and your irritated skin becomes red, swollen, itchy and painful. Betamethasone skin treatments work on your skin's cells to stop these chemicals being released. This reduces any swelling, redness and itching.
Your skin should start to get better after using betamethasone for a few days. If you're using cream, ointment or lotion, speak to your doctor if there is no improvement after 4 weeks, or if your skin gets worse at any time. Ask your doctor how long it should take to show an improvement if you are using the scalp foam or are using betamethasone on your face.
They will tell you what to do if it does not work. For long-term skin problems, such as eczema or psoriasis, you may need to use the skin treatments for a week or two, or sometimes for longer.
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